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These projects build on the multi-functionality allowed by 2DMs to demonstrate the advantages of combining e.g. biocompatibility, chemical stability, (bio-) sensing and actuating, and integration with flexible electronic technologies, in addition to versatile surface chemistry (for interface with biology) which allows for continuous health monitoring and built-in pharmacological interventions.

The aim is to offer new technology solutions exploiting the unique properties of 2D materials (2DM) that would reduce cost and increase the efficacy of diagnostics or therapies, or provide new diagnostics or therapies for which there is currently no solution. It would strengthen Europe’s industrial position in, early diagnostics, disease prediction and prevention, disease monitoring and reducing hospitalization time.



Proteases recently emerged as a promising new class of biomarkers with a broad diagnostic, prognostic and therapeutic potential for different human diseases including neurological and psychiatric diseases, several types of cancer, and immune system disorders. However, there is a lack of tools for real-time activity analysis of disease-related protease biomarkers.


2D-BioPAD is a cost-effective, non-invasive point of care/self-testing tool for the early and accurate prognosis (assistive diagnosis) of Alzheimer's Disease, with special focus on earlier stages such as Subjective or Mild Cognitive Impairment (SCI/MCI).

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